Doctors at NCR are conducting a research study for adults who have type 2 diabetes and are also overweight or living with obesity. The study is testing a new injectable medication that may help with weight loss.

The medication being studied is called Zenagamtide. It’s designed to act like two natural hormones in the body, GLP‑1 and amylin, which help regulate appetite, digestion, and blood sugar. By activating both pathways, this medication may help people feel full longer, and eat less, which can lead to weight loss. Participants in the study will receive either the study medication or a placebo (a shot with no active medication), along with one‑on‑one healthy lifestyle guidance from a dietitian. The goal is to see how well the medication helps reduce body weight.

18 or older

  • BMI > 27
  • No GLP-1s used in the last year
  • Must have type 2 diabetes* for >180 days and a Hb A1c between 7% and 10%
    *people with pre-diabetes are not eligible for this trial.

21 clinic visits & 7 phone calls over a period of 92 weeks

You will be reimbursed up to $2,750 if you complete the study visits

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