People who have a high blood cholesterol levels are often given a statin medication (e.g. Lipitor, Crestor, Zocor) to prevent a heart attack or stroke. Unfortunately, not everyone who is given a statin will achieve a blood cholesterol goal to achieve the best protection against having heart attack or stroke. Also, some people find that they have a hard time tolerating a statin. So scientists are constantly looking for new medications that can help out when these circumstances appear. We are currently helping to test several medications that can be given with or without lipid-modifying therapy; these new studies are described below.

#1.  Are you taking Zetia (ezetimibe), or a low dose statin, or only a diet to treat your high cholesterol? Doctors at National Clinical Research are studying an investigation product (IP) which is being added to Zetia for high blood cholesterol. The purpose of this study is to determine how much the new medication adds to the lowering of cholesterol over what is achieved with Zetia alone. Everyone participating in this study will receive given Zetia at no cost.

Key Inclusion / Exclusion Criteria:

  • Have a LDL Cholesterol level above 100 mg/dL if you are already receiving Zetia or a small dose statin OR a LDL cholesterol level above 120 mg/dL if you are only following a cholesterol lowering diet
  • Have a triglycerides level below 500 mg/dL

#2.  Are you taking a high dose statin or intolerant to statins, have heart disease and your LDL cholesterol is above 70?
Doctors at National Clinical Research are studying an investigation product (IP) in patients who have a history of heart disease (Coronary Artery Disease, Cardiovascular Disease or Peripheral Arterial Disease) and a LDL cholesterol above 70 on a statin or other lipid-modifying therapy if intolerant.  The purpose of this study is to determine how much the new medication adds to the lowering of cholesterol over what is achieved with the current therapy alone.

Key Inclusion / Exclusion Criteria:

  • History of heart attack, coronary bypass, stents, stroke or PAD
  • LDL above 70
  • Triglycerides less than 400

#3.  Are you taking a high dose statin or intolerant to statins and your LDL cholesterol is still above 100?
Doctors at National Clinical Research are studying an investigation product (IP) in patients who have a history Familial Hypercholesterolemia (FH) and a LDL cholesterol above 100 on a statin or other lipid-modifying therapy if intolerant.  The purpose of this study is to determine how much the new medication adds to the lowering of cholesterol over what is achieved with the current therapy alone.

Key Inclusion / Exclusion Criteria:

  • Familial Hypercholesterolemia (FH) with documented untreated LDL > 190
  • LDL above 100
  • Triglycerides less than 400

18+

Varies

Varies

Want to participate? Fill out the interest form! Click to Call Us!